The Direct C–H Difluoromethylation of Heteroarenes Based on the Photolysis of Hypervalent Iodine(III) Reagents That Contain Difluoroacetoxy Ligands
-
- Ryu Sakamoto
- Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan
-
- Hirotaka Kashiwagi
- Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan
-
- Keiji Maruoka
- Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan
書誌事項
- 公開日
- 2017-09-12
- 資源種別
- journal article
- DOI
-
- 10.1021/acs.orglett.7b02416
- 公開者
- American Chemical Society (ACS)
この論文をさがす
説明
In this letter, an efficient method for the photolytic generation of difluoromethyl radicals from [bis(difluoroacetoxy)iodo]benzene reagents is described. The present approach enables the introduction of difluoromethyl groups into various heteroarenes under mild conditions in the absence of any additional reagents or catalysts.
収録刊行物
-
- Organic Letters
-
Organic Letters 19 (19), 5126-5129, 2017-09-12
American Chemical Society (ACS)