Synergistic Catalysis of Ionic Brønsted Acid and Photosensitizer for a Redox Neutral Asymmetric α-Coupling of <i>N</i>-Arylaminomethanes with Aldimines

  • Daisuke Uraguchi
    Institute of Transformative Bio-Molecules (WPI-ITbM) and Department of Applied Chemistry, Graduate School of Engineering and ‡CREST, Japan Science and Technology Agency (JST), Nagoya University, Nagoya 464-8602, Japan
  • Natsuko Kinoshita
    Institute of Transformative Bio-Molecules (WPI-ITbM) and Department of Applied Chemistry, Graduate School of Engineering and ‡CREST, Japan Science and Technology Agency (JST), Nagoya University, Nagoya 464-8602, Japan
  • Tomohito Kizu
    Institute of Transformative Bio-Molecules (WPI-ITbM) and Department of Applied Chemistry, Graduate School of Engineering and ‡CREST, Japan Science and Technology Agency (JST), Nagoya University, Nagoya 464-8602, Japan
  • Takashi Ooi
    Institute of Transformative Bio-Molecules (WPI-ITbM) and Department of Applied Chemistry, Graduate School of Engineering and ‡CREST, Japan Science and Technology Agency (JST), Nagoya University, Nagoya 464-8602, Japan

書誌事項

公開日
2015-10-16
資源種別
journal article
DOI
  • 10.1021/jacs.5b09329
  • 10.1002/chin.201617085
公開者
American Chemical Society (ACS)

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説明

A redox neutral, highly enantioselective coupling between N-arylaminomethanes and N-sulfonyl aldimines was developed by harnessing the efficient catalysis of P-spiro chiral arylaminophosphonium barfate and a transition-metal photosensitizer under visible light irradiation. This mode of synergistic catalysis provides a powerful strategy for controlling the bond-forming processes of reactive radical intermediates.

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