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説明
Developing methods for stabilizing DNA nanostructures is a major challenge for next-generation nanofabrication, because stable DNA nanostructures are expected to work as building materials in the bottom-up assembly of functional biomolecules and nano-electronic components. Here we show the availability of cross-linking-type photoreaction with 3-cyanovinylcarbazole nucleosides (CNVKs) on DNA nanostructures. DNA double-crossover AB-staggered (DXAB) tiles including cross-linking molecules, CNVKs, self-assembled into two-dimensional (2D) periodic DNA arrays and were covalently connected by photo-cross-linking. The self-assembled DNA arrays before and after photo-cross-linking have been visualized by high-resolution, tapping mode atomic force microscopy (AFM) in buffer. The improvement of the heat tolerance of photo-cross-linked DNA arrays was confirmed by heating and visualizing the DNA nanostructures. The heat-resistant DNA arrays may expand the potential of DNA as a functional material in biotechnology and nanotechnology.
収録刊行物
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- Soft Matter
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Soft Matter 7 (22), 10931-, 2011
Royal Society of Chemistry (RSC)
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詳細情報 詳細情報について
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- CRID
- 1360002216874998912
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- ISSN
- 17446848
- 1744683X
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- 資料種別
- journal article
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- データソース種別
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- Crossref
- KAKEN
- OpenAIRE
