Budding and Fission of Cationic Binary Lipid Vesicles Induced by the Incorporation of Pyranine

  • Zhonghua Wang
    Graduate School of Materials Science, Nara Institute of Science and Technology
  • Kazuma Yasuhara
    Graduate School of Materials Science, Nara Institute of Science and Technology
  • Hiroshi Ito
    Graduate School of Materials Science, Nara Institute of Science and Technology
  • Masaru Mukai
    Graduate School of Materials Science, Nara Institute of Science and Technology
  • Jun-ichi Kikuchi
    Graduate School of Materials Science, Nara Institute of Science and Technology

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<jats:title>Abstract</jats:title> <jats:p>Pyranine, a multivalent anionic fluorescent dye, triggered the budding and production of small vesicles from giant vesicles that consisted of zwitterionic and cationic lipids. Calorimetric analysis and microscopic observations revealed that the binding of pyranine induced domain formations of the lipid bilayer followed by membrane fission.</jats:p>

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  • Chemistry Letters

    Chemistry Letters 39 (1), 54-55, 2009-12-12

    Oxford University Press (OUP)

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