Future therapy for hepatitis B virus infection

書誌事項

公開日
2015-08
資源種別
journal article
権利情報
  • http://www.springer.com/tdm
DOI
  • 10.1007/s12328-015-0590-y
公開者
Springer Science and Business Media LLC

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説明

We can now control hepatitis B virus infection by continuously administering nucleoside and nucleotide analogues such as entecavir and tenofovir. These drugs are generally safe and sufficiently effective, but future drugs are needed that can show off-treatment efficacy--in other words, eradication of latent hepatitis B virus DNA (covalently closed circular DNA) in the hepatocytes. This article is an overview of new drugs under development and some novel strategies to inhibit hepatitis B virus proliferation.

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