Sulfuryl Chloride as an Efficient Initiator for the Metal-Free Aerobic Cross-Dehydrogenative Coupling Reaction of Tertiary Amines

  • Arata Tanoue
    Department of Chemistry, School of Science, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan
  • Woo-Jin Yoo
    Department of Chemistry, School of Science, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan
  • Shu̅ Kobayashi
    Department of Chemistry, School of Science, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan

書誌事項

公開日
2014-04-11
資源種別
journal article
DOI
  • 10.1021/ol500661t
  • 10.1002/chin.201445169
公開者
American Chemical Society (ACS)

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説明

A metal-free cross-dehydrogenative (CDC) reaction of tertiary amines was developed using a catalytic amount of sulfuryl chloride (SO2Cl2) under mild aerobic conditions. On the basis of the nature of SO2Cl2, it was assumed that the reagent acts as a radical initiator to induce the metal-free CDC reaction via a radical-initiated autoxidation mechanism.

収録刊行物

  • Organic Letters

    Organic Letters 16 (9), 2346-2349, 2014-04-11

    American Chemical Society (ACS)

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