Guanidinium iodide-catalyzed oxidative α-nitroalkylation of β-ketoamides
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- Koji Yasui
- Department of Life Science and Biotechnology
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- Takanari Kato
- Department of Life Science and Biotechnology
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- Kohei Kojima
- Department of Life Science and Biotechnology
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- Kazuo Nagasawa
- Department of Life Science and Biotechnology
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説明
<p>Oxidative nitroalkylation of β-ketoamides and nitroalkanes, mediated by hypoiodide generated from <italic>tert</italic>-butyl hydrogen peroxide and a catalytic amount of guanidinium iodide, afforded the corresponding α-nitroalkyl-β-ketoamides in up to 97% yield.</p>
収録刊行物
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- Chemical Communications
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Chemical Communications 51 (12), 2290-2293, 2015
Royal Society of Chemistry (RSC)