A Lewis acid/metal amide hybrid as an efficient catalyst for carbon–carbon bond formation

DOI Web Site 研究データあり 被引用文献1件 参考文献20件 オープンアクセス

書誌事項

公開日
2014
資源種別
journal article
DOI
  • 10.1039/c4sc01332h
公開者
Royal Society of Chemistry (RSC)

この論文をさがす

説明

While Lewis acids and metal amides are among the most frequently used metal species, they are believed to be incompatible when combined. Here we describe a Lewis acid/metal amide hybrid, which contains electron-withdrawing groups and basic and bulky nitrogen functional groups in the same metal complex, as a novel catalyst. We have synthesized In(N(SiMe3)2)2Cl (In(HMDS)2Cl) and In(HMDS)2OTf as Lewis acid/metal amide hybrids, which showed excellent catalytic activity for the reaction of nitrones with terminal alkynes to give synthetically useful propargyl hydroxylamines. It is noted that neither the Lewis acids (InCl3, In(OTf)3) nor the metal amides (In(HMDS)3) have activity; only the hybrids worked well, and the catalytic activity of the hybrids was shown to be much higher than that of previously reported catalysts for this reaction. The concept of a Lewis acid/metal amide hybrid as a catalyst may be expanded to broad acid/base catalysis.

収録刊行物

  • Chem. Sci.

    Chem. Sci. 5 (10), 3958-3962, 2014

    Royal Society of Chemistry (RSC)

被引用文献 (1)*注記

もっと見る

参考文献 (20)*注記

もっと見る

関連研究データ

もっと見る

関連プロジェクト

もっと見る

詳細情報 詳細情報について

問題の指摘

ページトップへ