High incidence of metachronous advanced adenoma and cancer after endoscopic resection of colon polyps ≥20 mm in size
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- Naohisa Yoshida
- Department of Molecular Gastroenterology and Hepatology Kyoto Prefectural University of Medicine, Graduate School of Medical Science Singapore
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- Yuji Naito
- Department of Molecular Gastroenterology and Hepatology Kyoto Prefectural University of Medicine, Graduate School of Medical Science Singapore
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- Kewin Tien Ho Siah
- Department of Molecular Gastroenterology and Hepatology Kyoto Prefectural University of Medicine, Graduate School of Medical Science Singapore
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- Takaaki Murakami
- Department of Molecular Gastroenterology and Hepatology Kyoto Prefectural University of Medicine, Graduate School of Medical Science Singapore
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- Kiyoshi Ogiso
- Department of Molecular Gastroenterology and Hepatology Kyoto Prefectural University of Medicine, Graduate School of Medical Science Singapore
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- Ryohei Hirose
- Department of Molecular Gastroenterology and Hepatology Kyoto Prefectural University of Medicine, Graduate School of Medical Science Singapore
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- Yutaka Inada
- Department of Molecular Gastroenterology and Hepatology Kyoto Prefectural University of Medicine, Graduate School of Medical Science Singapore
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- Ken Inoue
- Department of Molecular Gastroenterology and Hepatology Kyoto Prefectural University of Medicine, Graduate School of Medical Science Singapore
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- Hideyuki Konishi
- Department of Molecular Gastroenterology and Hepatology Kyoto Prefectural University of Medicine, Graduate School of Medical Science Singapore
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- Munehiro Kugai
- Department of Gastroenterology Maizuru Medical Center Kyoto Japan
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- Yasutaka Morimoto
- Department of Gastroenterology Matsushita Memorial Hospital Osaka Japan
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- Daisuke Hasegawa
- Department of Gastroenterology Ayabe City Hospital Osaka Japan
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- Kazuyuki Kanemasa
- Department of Gastroenterology Nara City Hospital Nara Japan
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- Naoki Wakabayashi
- Department of Gastroenterology Otsu City Hospital Shiga Japan
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- Nobuaki Yagi
- Department of Gastroenterology Murakami Memorial Hospital Gifu Japan
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- Akio Yanagisawa
- Department of Surgical Pathology Graduate School of Medical Science Kyoto Japan
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- Yoshito Itoh
- Department of Molecular Gastroenterology and Hepatology Kyoto Prefectural University of Medicine, Graduate School of Medical Science Singapore
書誌事項
- 公開日
- 2015-11-16
- 資源種別
- journal article
- 権利情報
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- http://onlinelibrary.wiley.com/termsAndConditions#vor
- DOI
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- 10.1111/den.12551
- 公開者
- Wiley
この論文をさがす
説明
<jats:sec><jats:title>Background and Aim</jats:title><jats:p>There are limited studies on incidence rates of metachronous neoplastic lesions after resecting large colorectal polyps. In the present study, we analyzed metachronous lesions after endoscopic resection of colorectal polyps ≥20 mm in size.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>We retrospectively analyzed consecutive patients who underwent endoscopic resection of polyps from 2006 to 2013 at two affiliated hospitals. All patients underwent at least two total colonoscopies before follow up to ensure minimal missed polyps. Only patients who had follow‐up colonoscopy annually after resection were recruited. We separated patients according to size of polyp resected; there were 239 patients in the ≥20‐mm group and 330 patients in the <20‐mm group. Clinical characteristics and cumulative rates of metachronous advanced adenoma and cancer in both groups were analyzed. Advanced adenoma was defined as a neoplastic lesion ≥10 mm in size and adenoma with a villous component.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Cumulative rate of development of metachronous advanced adenoma and cancer in the ≥20‐mm group was significantly higher than in the <20‐mm group (22.9% <jats:italic>vs</jats:italic> 9.5%, <jats:italic>P</jats:italic> < 0.001) at 36 months. There was also more development of small polyps 5–9 mm in the ≥20‐mm group than in the <20‐mm group (45.2% <jats:italic>vs</jats:italic> 28.8%, <jats:italic>P</jats:italic> < 0.001). With respect to metachronous lesions, there were more right‐sided colonic lesions in the ≥20‐mm group than in the <20‐mm group (78.8% <jats:italic>vs</jats:italic> 50.0%, <jats:italic>P</jats:italic> = 0.015).</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>High incidence rates of development of metachronous neoplastic lesions were detected after resection of colorectal polyps ≥20 mm in size.</jats:p></jats:sec>
収録刊行物
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- Digestive Endoscopy
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Digestive Endoscopy 28 (2), 194-202, 2015-11-16
Wiley