CELLULAR UPTAKE BEHAVIOR OF FLUORESCEIN: INTERCALATED LAYERED DOUBLE HYDROXIDE

DOI Web Site 被引用文献1件 参考文献10件
  • MIYUKI TANAKA
    Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1, Katahira, Aoba-ku, Sendai 980-8577, Japan
  • SUMIO AISAWA
    Graduate School of Engineering, Iwate University, Morioka 020-8551, Japan
  • HIDETOSHI HIRAHARA
    Graduate School of Engineering, Iwate University, Morioka 020-8551, Japan
  • EIICHI NARITA
    Graduate School of Engineering, Iwate University, Morioka 020-8551, Japan
  • SHU YIN
    Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1, Katahira, Aoba-ku, Sendai 980-8577, Japan
  • TSUGIO SATO
    Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1, Katahira, Aoba-ku, Sendai 980-8577, Japan

書誌事項

公開日
2012-06
資源種別
journal article
DOI
  • 10.1142/s179360471260003x
公開者
World Scientific Pub Co Pte Lt

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説明

<jats:p> In order to define the ability of layered double hydroxide (LDH) as materials for drug delivery, fluorescein (Fluo) anion intercalated LDH (Fluo/LDH) was synthesized by hydrothermal treatment and observed the cellular uptake of the Fluo/LDH for mammalian cell (L929). The synthesized Fluo/LDH showed a LDH structure, high fluorescence and low cytotoxicity. According to the fluorescence, confocal and TEM images of cells, the Fluo/LDH seemed to be internalized into the L929 cell by cellular endocytosis and dissolved inside the cell to exhibit the fluorescence of cellular cytoplasm. </jats:p>

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