Membrane Transport: Ionic Environments, Signal Transduction, and Development of Therapeutic Targets
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- Akio Tomoda
- Tokyo Medical University, Tokyo 160-0022, Japan
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- Yoshinori Marunaka
- Departments of Molecular Cell Physiology and Bio-Ionomics, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan
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- Douglas C. Eaton
- Department of Physiology, Emory University School of Medicine, Atlanta, GA 30322, USA
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- Anuwat Dinudom
- Department of Physiology, Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia
書誌事項
- 公開日
- 2015
- 資源種別
- journal article
- 権利情報
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- http://creativecommons.org/licenses/by/3.0/
- DOI
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- 10.1155/2015/581626
- 公開者
- Wiley
この論文をさがす
説明
Membrane transport plays a critical role in producing ionic environments in both intracellular and extracellular spaces that are necessary for cellular signal transduction. The importance of membrane transport implies that any abnormality may lead to pathophysiological conditions and often to specific diseases. This also means that membrane transporters, including ion channels and transporters, are very important therapeutic targets in several diseases such as cardiovascular disorders, hypertension, dementia, metabolic syndrome associated with diabetes mellitus, and cancer. Thus, many researchers have been investigating regulatory mechanisms of membrane transport with an aim to develop new therapies for treating transport disorders found in various diseases.
収録刊行物
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- BioMed Research International
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BioMed Research International 2015 1-2, 2015
Wiley
