Phosphorylated Pullulan Coating Enhances Titanium Implant Osseointegration in a Pig Model
書誌事項
- 公開日
- 2017-03
- 資源種別
- journal article
- DOI
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- 10.11607/jomi.5074
- 公開者
- Quintessence Publishing
この論文をさがす
説明
To investigate the effect of coating a titanium implant surface with a phosphorylated exopolysaccharide, pullulan, on the peri-implant bone formation and implant osseointegration.Implants were placed in the skull bone of 12 domestic pigs and healed for 1 or 3 months. Osseointegration of (un)coated implants was evaluated by quantitative histology (peri-implant bone fraction [BF] and bone-to-implant-contact [BIC]). The Wilcoxon-Mann-Whitney test with α = .05 was used to statistically compare BF and BIC of the coated and uncoated implants.Significantly more BF was observed surrounding pullulan-coated implants compared with uncoated implants (P.05) and for both healing periods (P.05). BIC was positively affected by the exopolysaccharide coating, with significantly more BIC after the 3-month healing period compared with the uncoated implant (P.05). Furthermore, BIC remained stable over time for the coated implants, while it significantly decreased for the uncoated ones (P.05).These findings reveal the capacity of functionalizing the titanium implant surface with phosphorylated pullulan to improve the mineralization of the implant-bone interface.
収録刊行物
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- The International Journal of Oral & Maxillofacial Implants
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The International Journal of Oral & Maxillofacial Implants 32 (2), 282-290, 2017-03
Quintessence Publishing
