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- H. Anzai
- Frontier Research Institute of Interdisciplinary Sciences, Tohoku University, Sendai, Japan
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- Y. Yoshida
- Graduate School of Engineering, Tohoku University, Sendai, Japan
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- S. Sugiyama
- Department of Neurosurgery, Kohnan Hospital, Sendai, Japan
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- H. Endo
- Department of Neurosurgery, Kohnan Hospital, Sendai, Japan
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- Y. Matsumoto
- Department of Neuroendovascular Therapy, Kohnan Hospital, Sendai, Japan
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- M. Ohta
- Institute of Fluid Science, Tohoku University, Sendai, Japan
書誌事項
- 公開日
- 2015-09-22
- 資源種別
- journal article
- DOI
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- 10.3233/thc-151007
- 公開者
- SAGE Publications
この論文をさがす
説明
Optimal design of stents for a cerebral aneurysm is desired for efficient flow reduction in the aneurysm.In this study, we aimed to optimize stent design at several porosities, estimate the influence of stent design on aneurysm flow, and evaluate the ability of stents to reduce flow.Stent models were constructed as sets of squares or rectangles in the necks of a two-dimensional (2D) and realistic aneurysm. Then, automated optimization was performed using a combination of simulated annealing and lattice Boltzmann flow simulation.By simulated annealing, stents were gradually modified to reduce the average velocity in an aneurysm. As a result of optimization, stents of all porosities demonstrated an inhomogeneous distribution with dense struts in the inflow area. Flow reduction was increased compared with the initial stent. Under the condition of high porosity, flow reduction by the stent drastically increased as porosity decreased. Under low porosity, the increase of velocity reduction was moderate even as porosity decreased.Optimization can enhance flow reduction by stents. However, the increase in reduction associated with decreasing porosity is moderate under lower-porosity conditions. This threshold may help in the choice of stent porosity for each specific aneurysm.
収録刊行物
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- Technology and Health Care
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Technology and Health Care 23 (5), 547-556, 2015-09-22
SAGE Publications