Hypocomplementemia is related to elevated serum levels of IgG subclasses other than IgG4 in IgG4-related kidney disease
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- Yuhei Fujisawa
- Department of Cardiovascular and Internal Medicine, Division of Rheumatology, Kanazawa University Graduates School of Medicine, Kanazawa, Japan
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- Ichiro Mizushima
- Department of Internal Medicine, Division of Rheumatology, Kanazawa University Hospital, Kanazawa, Japan
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- Kazunori Yamada
- Department of Internal Medicine, Division of Rheumatology, Kanazawa University Hospital, Kanazawa, Japan
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- Motohisa Yamamoto
- Department of Rheumatology and Clinical Immunology, Sapporo Medical University School of Medicine, Sapporo, Japan
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- Takako Saeki
- Department of Internal Medicine, Nagaoka Red Cross Hospital, Niigata, Japan
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- Shoko Matsui
- Health Administration Center, University of Toyama, Toyama, Japan
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- Syunsuke Tsuge
- Department of Internal Medicine, Division of Rheumatology, Kanazawa University Hospital, Kanazawa, Japan
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- Satoshi Hara
- Department of Internal Medicine, Division of Rheumatology, Kanazawa University Hospital, Kanazawa, Japan
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- Kiyoaki Ito
- Department of Internal Medicine, Division of Rheumatology, Kanazawa University Hospital, Kanazawa, Japan
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- Hiroshi Fujii
- Department of Internal Medicine, Division of Rheumatology, Kanazawa University Hospital, Kanazawa, Japan
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- Hiroki Takahashi
- Department of Rheumatology and Clinical Immunology, Sapporo Medical University School of Medicine, Sapporo, Japan
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- Hideki Nomura
- Department of General Medicine, Kanazawa University Hospital, Kanazawa, Japan
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- Shigeyuki Kawa
- Department of Internal Medicine, Matsumoto Dental University, Shiojiri, Japan
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- Mitsuhiro Kawano
- Department of Internal Medicine, Division of Rheumatology, Kanazawa University Hospital, Kanazawa, Japan
書誌事項
- 公開日
- 2020-01-13
- 資源種別
- journal article
- DOI
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- 10.1080/14397595.2019.1709942
- 公開者
- Oxford University Press (OUP)
この論文をさがす
説明
This study investigated the clinical features of IgG4-RKD patients with hypocomplementemia compared with those without it, so as to clarify the factors related to hypocomplementemia.In this single-center retrospective study, we analyzed the clinical features of 25 patients with IgG4-RKD according to the presence/absence of hypocomplementemia. Additionally, we validated the results of a single-center study in a separate large multicenter cohort of 328 patients with IgG4-RD, and searched for factors related to hypocomplementemia.Serum IgG levels (The present study suggests that hypocomplementemia is associated with elevation of IgG subclasses other than IgG4 including IgG1 in IgG4-RKD.
収録刊行物
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- Modern Rheumatology
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Modern Rheumatology 31 (1), 241-248, 2020-01-13
Oxford University Press (OUP)
