Development of functionalized peptides for efficient inhibition of myostatin by selective photooxygenation
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- Hideyuki Okamoto
- Department of Medicinal Chemistry
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- Atsuhiko Taniguchi
- Department of Medicinal Chemistry
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- Shoya Usami
- Department of Medicinal Chemistry
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- Masahiro Katsuyama
- Department of Medicinal Chemistry
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- Sho Konno
- Department of Medicinal Chemistry
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- Akihiro Taguchi
- Department of Medicinal Chemistry
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- Kentaro Takayama
- Department of Medicinal Chemistry
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- Yoshio Hayashi
- Department of Medicinal Chemistry
説明
<p>Functionalized peptides which consist of myostatin-binding peptide and on/off-switchable catalyst efficiently inhibit myostatin by selective photooxygenation, leading to a therapeutic strategy for muscular atrophic disorders.</p>
収録刊行物
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- Organic & Biomolecular Chemistry
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Organic & Biomolecular Chemistry 19 (1), 199-207, 2021
Royal Society of Chemistry (RSC)
