Parvovirus-Derived Endogenous Viral Elements in Two South American Rodent Genomes
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- Gloria Arriagada
- Universidad Andres Bello, Departamento de Ciencias Biologicas, Facultad de Ciencias Biologicas, Quillota 980, Viña del Mar, Chile
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- Robert J. Gifford
- MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom
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- K. L. Beemon
- editor
説明
<jats:title>ABSTRACT</jats:title> <jats:p> We describe endogenous viral elements (EVEs) derived from parvoviruses (family <jats:named-content content-type="genus-species">Parvoviridae</jats:named-content> ) in the genomes of the long-tailed chinchilla ( <jats:named-content content-type="genus-species">Chinchilla lanigera</jats:named-content> ) and the degu ( <jats:named-content content-type="genus-species">Octodon degus</jats:named-content> ). The novel EVEs include dependovirus-related elements and representatives of a clearly distinct parvovirus lineage that also has endogenous representatives in marsupial genomes. In the degu, one dependovirus-derived EVE was found to carry an intact reading frame and was differentially expressed <jats:italic>in vivo</jats:italic> , with increased expression in the liver. </jats:p>
収録刊行物
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- Journal of Virology
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Journal of Virology 88 (20), 12158-12162, 2014-10-15
American Society for Microbiology
