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- Ming-Chi Lai
- Department of Pediatrics, Chi Mei Medical Center, Tainan, Taiwan
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- San-Nan Yang
- Graduate Institute of Medicine, Kaohsiung Medical University, No. 100, Zihyou 1st Road, Sanmin District Kaohsiung City 807, Taiwan
説明
<jats:p>Perinatal hypoxic-ischemic encephalopathy (HIE) is an important cause of brain injury in the newborn and can result in long-term devastating consequences. Perinatal hypoxia is a vital cause of long-term neurologic complications varying from mild behavioural deficits to severe seizure, mental retardation, and/or cerebral palsy in the newborn. In the mammalian developing brain, ongoing research into pathophysiological mechanism of neuronal injury and therapeutic strategy after perinatal hypoxia is still limited. With the advent of promising therapy of hypothermia in HIE, this paper reviews the pathophysiology of HIE and the future potential neuroprotective strategies for clinical potential for hypoxia sufferers.</jats:p>
収録刊行物
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- Journal of Biomedicine and Biotechnology
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Journal of Biomedicine and Biotechnology 2011 1-6, 2011
Hindawi Limited
