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Glioblastoma multiforme of the pineal region: case report
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- Emerson Leandro Gasparetto
- Universidade Federal do Parana
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- Danny Warszawiak
- Universidade Federal do Parana
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- Guilherme Pradi Adam
- Universidade Federal do Parana
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- Luiz Fernando Bleggi-Torres
- Universidade Federal do Parana
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- Arnolfo de Carvalho Neto
- Universidade Federal do Parana
Description
<jats:p>PURPOSE: pineal region tumors are uncommon, and comprise more frequently three categories: germ cell, parenchymal cell and glial tumors. Most pineal gliomas are low-grade astrocytomas. Glioblastoma multiforme, the most aggressive and common brain tumor, is extremely rare at this location with only few cases reported. CASE DESCRIPTION: a 29-year-old woman with a two month history of headache, nuchal pain, fever, nausea and seizures and physical examination showing nuchal rigidity, generalized hypotony, hypotrophy and hyper-reflexia, Babinski sign and left VI cranial par palsy. CT scan examination revealed a ill-defined hypodense lesion at the pineal region with heterogeneous contrast enhancement. MRI showed a lesion at the pineal region infiltrating the right thalamic region. The patient underwent a right craniotomy with partial resection of the mass. The histological examination of paraffin-embedded material defined the diagnosis of glioblastoma multiforme. Post-operative radiotherapy was indicated but the patient refused the treatment and died two months afterwards. CONCLUSION: in spite of its rarity at this location, glioblastoma multiforme should be considered in the differential diagnosis of aggressive lesions at the pineal region.</jats:p>
Journal
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- Arquivos de Neuro-Psiquiatria
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Arquivos de Neuro-Psiquiatria 61 (2B), 468-472, 2003-06
FapUNIFESP (SciELO)
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Details 詳細情報について
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- CRID
- 1360011144346332928
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- ISSN
- 0004282X
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- Data Source
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- Crossref