Selective Photothermolysis: Precise Microsurgery by Selective Absorption of Pulsed Radiation

DOI Web Site 被引用文献109件
  • R. Rox Anderson
    Department of Dermatology, Harvard Medical School, Massachusetts General Hospital, Boston 02114
  • John A. Parrish
    Department of Dermatology, Harvard Medical School, Massachusetts General Hospital, Boston 02114

書誌事項

公開日
1983-04-29
DOI
  • 10.1126/science.6836297
公開者
American Association for the Advancement of Science (AAAS)

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説明

<jats:p> Suitably brief pulses of selectively absorbed optical radiation can cause selective damage to pigmented structures, cells, and organelles in vivo. Precise aiming is unnecessary in this unique form of radiation injury because inherent optical and thermal properties provide target selectivity. A simple, predictive model is presented. Selective damage to cutaneous microvessels and to melanosomes within melanocytes is shown after 577-nanometer (3 × 10 <jats:sup>-7</jats:sup> second) and 351-nanometer (2 × 10 <jats:sup>-8</jats:sup> second) pulses, respectively. Hemodynamic, histological, and ultrastructural responses are discussed. </jats:p>

収録刊行物

  • Science

    Science 220 (4596), 524-527, 1983-04-29

    American Association for the Advancement of Science (AAAS)

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