IMMUNOLOGICAL STUDIES OF ONCHOCERCIASIS IN GUATEMALA

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  • Tomio Akiyama
    Department of Dermatology Nagasaki University School of Medicine Nagasaki 852 Japan (Director: Prof. Hikotaro Yoshida)
  • Nobuo Ushijima
    Department of Dermatology Nagasaki University School of Medicine Nagasaki 852 Japan (Director: Prof. Hikotaro Yoshida)
  • Sadao Anan
    Department of Dermatology Nagasaki University School of Medicine Nagasaki 852 Japan (Director: Prof. Hikotaro Yoshida)
  • Shigeo Nonaka
    Department of Dermatology Nagasaki University School of Medicine Nagasaki 852 Japan (Director: Prof. Hikotaro Yoshida)
  • Hikotaro Yoshida
    Department of Dermatology Nagasaki University School of Medicine Nagasaki 852 Japan (Director: Prof. Hikotaro Yoshida)
  • Guillermo Efrain Zea Flores
    Department of Dermatology Nagasaki University School of Medicine Nagasaki 852 Japan (Director: Prof. Hikotaro Yoshida)

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Other Title
  • I. IMMUNOGLOBULIN LEVELS IN GUATEMALAN ONCHOCERCIASIS

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<jats:title>ABSTRACT</jats:title><jats:p>The serum levels of the four immunoglobulins, IgG, IgA, IgM and IgE, in Guatemalan onchocerciasis patients were determined quantitatively using a laser immunoassay system or radioimmunosorbent test.</jats:p><jats:p>The IgG and IgE levels in Guatemalan onchocerciasis patients positive for <jats:italic>Onchocerca volvulus microfilariae</jats:italic> were significantly higher than the levels in Guatemalan controls negative for <jats:italic>microfilariae</jats:italic> and in healthy Japanese controls. But, no differences in the levels of IgA and IgM were obtained between the Guatemalan onchocerciasis patient group and the two control groups.</jats:p>

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