Reproductive History of Mothers of Children with Solitary, Nonsyndromic Cleft Lip and/or Palate
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- Bente Felix-Schollaart
- Department of Orthodontics, Academic Center Dentistry Amsterdam, Louwesweg 1, 1066 EA Amsterdam, The Netherlands. Andreas Hospital in Amsterdam, The Netherlands.
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- Jan B. Hoeksma
- Department of Orthodontics, Academic Center Dentistry Amsterdam, Louwesweg 1, 1066 EA Amsterdam, The Netherlands. Andreas Hospital in Amsterdam, The Netherlands.
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- Jean Paul Van De Velde
- Department of Orthodontics, Academic Center Dentistry Amsterdam, Louwesweg 1, 1066 EA Amsterdam, The Netherlands. Andreas Hospital in Amsterdam, The Netherlands.
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- Jerôme I. Puyenbroek
- Department of Orthodontics, Academic Center Dentistry Amsterdam, Louwesweg 1, 1066 EA Amsterdam, The Netherlands. Andreas Hospital in Amsterdam, The Netherlands.
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- Birte Prahl-Andersen
- Department of Orthodontics, Academic Center Dentistry Amsterdam, Louwesweg 1, 1066 EA Amsterdam, The Netherlands. Andreas Hospital in Amsterdam, The Netherlands.
説明
<jats:p> The reproductive history was studied to evaluate if the three types of solitary, nonsyndromic clefts: cleft lip (CL), cleft lip and palate (CLP), and cleft palate (CP) are homogeneous entities. Occurrence of fetal loss, maternal health, and drug consumption of the mother during the pregnancy were compared in cases involving three types of clefts. Data was gathered from 87 children with clefts, 55 males and 32 females. Spontaneous abortions and vaginal bleeding were found to occur significantly more often in the (older) mother of a CLP child. This suggests that the factors involved in the etiology of CLP differ from the factors involved in CL and CP. Therefore, grouping of data of the three types of clefts in studies on the etiology should be avoided. </jats:p>
収録刊行物
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- The Cleft Palate Craniofacial Journal
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The Cleft Palate Craniofacial Journal 29 (5), 470-474, 1992-09
SAGE Publications
