Simple surface modification of poly(ε-caprolactone) for apatite deposition from simulated body fluid
書誌事項
- 公開日
- 2005-05
- 権利情報
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- https://www.elsevier.com/tdm/userlicense/1.0/
- https://www.elsevier.com/legal/tdmrep-license
- DOI
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- 10.1016/j.biomaterials.2004.07.048
- 公開者
- Elsevier BV
この論文をさがす
説明
Poly(epsilon-caprolactone) (PCL) with a bone-like apatite layer bound to its surface could be useful as a scaffold for tissue engineering applications. In the present study, the surface of PCL was treated with aqueous NaOH to introduce carboxylate groups onto the surface. The NaOH-treated material was subsequently dipped in aqueous CaCl(2) and K(2)HPO(4).3H(2)O alternately three times to deposit apatite nuclei on the surface. The surface-modified material successfully formed a dense and uniform bone-like surface apatite layer after incubation for 24 h in simulated body fluid with ion concentrations approximately equal to those of human blood plasma.
収録刊行物
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- Biomaterials
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Biomaterials 26 (15), 2407-2413, 2005-05
Elsevier BV