Pharmacotherapeutic Effects of Toki-shakuyaku-san on Leukorrhagia in Young Women

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  • Shinobu Sakamoto
    Department of Endocrinology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113, Japan
  • Hideki Kudo
    Department of Endocrinology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113, Japan
  • Satoe Suzuki
    Department of Endocrinology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113, Japan
  • Shuji Sassa
    Department of Endocrinology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113, Japan
  • Shintarou Yoshimura
    Department of Endocrinology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113, Japan
  • Tohru Nakayama
    Department of Endocrinology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113, Japan
  • Masatoshi Maemura
    Department of Endocrinology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113, Japan
  • Tadasu Mitamura
    Department of Endocrinology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113, Japan
  • Zeng Qi
    Department of Endocrinology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113, Japan
  • Xie-dong Liu
    Department of Endocrinology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113, Japan
  • Youichi Yagishita
    Division of Medical Information, Tsumura Co. Ltd., Tokyo, Japan
  • Akira Asai
    Division of Medical Information, Tsumura Co. Ltd., Tokyo, Japan

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<jats:p> Toki-shakuyaku-san is a traditional Chinese herbal prescriptions that is composed of 6 herbal plants, i.e., peony root, atractylodes lancea rhizome, alisma rhizome, hoelen, cnidium rhizome and Japanese angelica root. Administration with Toki-shakuyaku-san normalized irregular menstrual cycle, healed cervical pseudo-erosion and reduced leukorrhagia in young women who had insufficient luteal function. </jats:p>

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