G-ribo: A new structural motif in ribosomal RNA
Abstract
<jats:p>Analysis of the available crystal structures of the ribosome and of its subunits has revealed a new RNA motif that we call G-ribo. The motif consists of two double helices positioned side-by-side and connected by an unpaired region. The juxtaposition of the two helices is kept by a complex system of tertiary interactions spread over several layers of stacked nucleotides. In the center of this arrangement, the ribose of a nucleotide from one helix is specifically packed with the ribose and the minor-groove edge of a guanosine from the other helix. In total, we found eight G-ribo motifs in both ribosomal subunits. The location of these motifs suggests that at least some of them play an important role in the formation of the ribosome structure and/or in its function.</jats:p>
Journal
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- RNA
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RNA 13 (4), 549-554, 2007-02-05
Cold Spring Harbor Laboratory
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Keywords
Details 詳細情報について
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- CRID
- 1360011145202994688
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- ISSN
- 14699001
- 13558382
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- Data Source
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- Crossref