Investigating changes in the gas-phase conformation of Antithrombin III upon binding of Arixtra using traveling wave ion mobility spectrometry (TWIMS)
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- Yuejie Zhao
- University of Georgia
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- Arunima Singh
- University of Georgia
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- Lingyun Li
- Rensselaer Polytechnic Institute
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- Robert J. Linhardt
- Rensselaer Polytechnic Institute
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- Yongmei Xu
- University of North Carolina
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- Jian Liu
- University of North Carolina
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- Robert J. Woods
- University of Georgia
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- I. Jonathan Amster
- University of Georgia
Description
<p>We validate the utility of ion mobility to measure protein conformational changes induced by the binding of glycosaminoglycan ligands.</p>
Journal
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- The Analyst
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The Analyst 140 (20), 6980-6989, 2015
Royal Society of Chemistry (RSC)
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Details 詳細情報について
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- CRID
- 1360011146144572160
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- ISSN
- 13645528
- 00032654
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- Data Source
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- Crossref