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- Hiroki Higashiyama
- Department of Physiological Chemistry and Metabolism, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan;
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- Daisuke Koyabu
- Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Kowloon, Hong Kong;
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- Tatsuya Hirasawa
- Department of Earth and Planetary Science, Graduate School of Science, The University of Tokyo, Tokyo 113-0033, Japan;
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- Ingmar Werneburg
- Senckenberg Centre for Human Evolution and Palaeoenvironment, Eberhard Karls Universität Tübingen, Tübingen 72076, Germany;
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- Shigeru Kuratani
- Evolutionary Morphology Laboratory, RIKEN Cluster for Pioneering Research, Kobe 650-0047, Japan;
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- Hiroki Kurihara
- Department of Physiological Chemistry and Metabolism, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan;
説明
<jats:title>Significance</jats:title> <jats:p>The anatomical framework of the jaw has traditionally been thought to be highly conserved among vertebrates. However, here we show that the therian-unique face (muzzle) evolved via a drastic alteration of the common pattern of the tetrapod jaw. Through comparative morphological and developmental analyses, we demonstrated that the therian mammal’s premaxilla (rostral-most upper jawbone) is derived from the maxillary prominence of the mandibular arch. The developmental primordium that produces the premaxilla in nonmammalian tetrapods rarely contributes to the upper jaw in therian mammals but rather forms a motile nose. We propose that these previously unrecognized rearrangements allowed key innovations such as the highly sensitive tactile perception and olfactory function in mammalian evolution.</jats:p>
収録刊行物
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- Proceedings of the National Academy of Sciences
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Proceedings of the National Academy of Sciences 118 (44), 2021-10-29
Proceedings of the National Academy of Sciences