Relationship between temporal changes of endometrial blood flow impedance during natural and hormone replacement cycles and prediction of pregnancy during vitrified‐warmed embryo transfer
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- Kuniaki Ota
- Fukushima Medical Center for Children and Women Fukushima Medical University Fukushima Japan
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- Satoru Shiraishi
- Department of Obstetrics and Gynecology Nasu Red Cross Hospital Tochigi Japan
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- Toshifumi Takahashi
- Fukushima Medical Center for Children and Women Fukushima Medical University Fukushima Japan
書誌事項
- 公開日
- 2021-01-04
- 資源種別
- journal article
- 権利情報
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- http://onlinelibrary.wiley.com/termsAndConditions#vor
- DOI
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- 10.1111/jog.14637
- 公開者
- Wiley
この論文をさがす
説明
<jats:title>Abstract</jats:title><jats:sec><jats:title>Aim</jats:title><jats:p>This study aimed to examine the relationship between the temporal changes in endometrial blood flow impedance during natural and hormone replacement therapy (HRT) cycles and clinical outcomes of vitrified‐warmed embryo transfer (ET).</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>This retrospective observational cohort study included 60 women, 28 with natural, and 32 with HRT cycles, who underwent vitrified‐warmed ET. Uterine radial artery resistance index (RA‐RI) was measured during the natural and HRT cycles at the following time points: early follicular phase, day of the human chorionic gonadotropin injection during a natural cycle or day of progesterone administration during an HRT cycle, and day of ET.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>The clinical pregnancy rates of the natural and HRT cycles were 32.1% and 34.4%, respectively. The RA‐RI at the early follicular phase was significantly lower in the pregnant group than in the nonpregnant group with natural but not HRT cycles (<jats:italic>p</jats:italic> = 0.04). The odds ratio for pregnancy was 0.70 (95% confidence interval [CI], 0.52–0.95) when the RA‐RI value at the early follicular phase was increased by 0.01 in the natural cycle. With the natural cycle, the area under the receiver‐operating characteristic curves for the RA‐RI at the early follicular phase with a threshold of 0.68 was 0.75 (95% CI, 0.57–0.93), and the positive and negative predictive values were 0.53 (95% CI, 0.37–0.59) and 0.92 (0.74–0.99), respectively.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>RA‐RI at the early follicular phase might be an effective and useful tool for deciding between natural or HRT cycles for vitrified‐warmed ET.</jats:p></jats:sec>
収録刊行物
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- Journal of Obstetrics and Gynaecology Research
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Journal of Obstetrics and Gynaecology Research 47 (3), 1052-1063, 2021-01-04
Wiley
