Biopolymer-based strategies in the design of smart medical devices and artificial organs

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  • Lina Altomare
    Department of Chemistry, Materials and Chemical Engineering “Giulio Natta,” Politecnico di Milano, Milano, Italy
  • Lorenzo Bonetti
    Department of Chemistry, Materials and Chemical Engineering “Giulio Natta,” Politecnico di Milano, Milano, Italy
  • Chiara E Campiglio
    Department of Chemistry, Materials and Chemical Engineering “Giulio Natta,” Politecnico di Milano, Milano, Italy
  • Luigi De Nardo
    Department of Chemistry, Materials and Chemical Engineering “Giulio Natta,” Politecnico di Milano, Milano, Italy
  • Lorenza Draghi
    Department of Chemistry, Materials and Chemical Engineering “Giulio Natta,” Politecnico di Milano, Milano, Italy
  • Francesca Tana
    Department of Chemistry, Materials and Chemical Engineering “Giulio Natta,” Politecnico di Milano, Milano, Italy
  • Silvia Farè
    Department of Chemistry, Materials and Chemical Engineering “Giulio Natta,” Politecnico di Milano, Milano, Italy

Abstract

<jats:p> Advances in regenerative medicine and in modern biomedical therapies are fast evolving and set goals causing an upheaval in the field of materials science. This review discusses recent developments involving the use of biopolymers as smart materials, in terms of material properties and stimulus-responsive behavior, in the presence of environmental physico-chemical changes. An overview on the transformations that can be triggered in natural-based polymeric systems (sol–gel transition, polymer relaxation, cross-linking, and swelling) is presented, with specific focus on the benefits these materials can provide in biomedical applications. </jats:p>

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