Top-Down N-Doped Carbon Quantum Dots for Multiple Purposes: Heavy Metal Detection and Intracellular Fluorescence
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- Francesca Limosani
- Department of Industrial Engineering, University of Rome Tor Vergata, Viale del Politecnico 1, 00133 Rome, Italy
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- Elvira Maria Bauer
- Institute of Structure of Matter (CNR-ISM), Italian National Research Council, Via Salaria km 29.3, 00015 Monterotondo, RM, Italy
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- Daniele Cecchetti
- Department of Chemical Science and Technologies, University of Rome Tor Vergata, Via della Ricerca Scientifica 1, 00133 Rome, Italy
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- Stefano Biagioni
- Department of Biology and Biotechnology “Charles Darwin”, Sapienza University of Rome, P.le A. Moro, 00185 Rome, Italy
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- Viviana Orlando
- Department of Biology and Biotechnology “Charles Darwin”, Sapienza University of Rome, P.le A. Moro, 00185 Rome, Italy
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- Roberto Pizzoferrato
- Department of Industrial Engineering, University of Rome Tor Vergata, Viale del Politecnico 1, 00133 Rome, Italy
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- Paolo Prosposito
- Department of Industrial Engineering, University of Rome Tor Vergata, Viale del Politecnico 1, 00133 Rome, Italy
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- Marilena Carbone
- Department of Chemical Science and Technologies, University of Rome Tor Vergata, Via della Ricerca Scientifica 1, 00133 Rome, Italy
書誌事項
- 公開日
- 2021-08-31
- 権利情報
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- https://creativecommons.org/licenses/by/4.0/
- DOI
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- 10.3390/nano11092249
- 公開者
- MDPI AG
説明
<jats:p>In the present study, we successfully synthesized N-doped carbon quantum dots (N-CQDs) using a top-down approach, i.e., hydroxyl radical opening of fullerene with hydrogen peroxide, in basic ambient using ammonia for two different reaction times. The ensuing characterization via dynamic light scattering, SEM, and IR spectroscopy revealed a size control that was dependent on the reaction time, as well as a more pronounced -NH2 functionalization. The N-CQDs were probed for metal ion detection in aqueous solutions and during bioimaging and displayed a Cr3+ and Cu2+ selectivity shift at a higher degree of -NH2 functionalization, as well as HEK-293 cell nuclei marking.</jats:p>
収録刊行物
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- Nanomaterials
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Nanomaterials 11 (9), 2249-, 2021-08-31
MDPI AG