Molecular mechanisms underlying metamorphosis in the most-ancestral winged insect

  • Genta Okude
    Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo 113-0033, Japan
  • Minoru Moriyama
    Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba 305-8566, Japan
  • Ryouka Kawahara-Miki
    NODAI Genome Research Center, Tokyo University of Agriculture, Tokyo 156-8502, Japan
  • Shunsuke Yajima
    NODAI Genome Research Center, Tokyo University of Agriculture, Tokyo 156-8502, Japan
  • Takema Fukatsu
    Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo 113-0033, Japan
  • Ryo Futahashi
    Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba 305-8566, Japan

書誌事項

公開日
2022-02-25
資源種別
journal article
権利情報
  • https://creativecommons.org/licenses/by/4.0/
DOI
  • 10.1073/pnas.2114773119
公開者
Proceedings of the National Academy of Sciences

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説明

<jats:title>Significance</jats:title> <jats:p> As caterpillars metamorphose to butterflies, insects change their appearance dramatically through metamorphosis. Some insects have an immobile pupal stage for morphological remodeling (homometaboly). Other insects, such as cockroaches, have no pupal stage, and the juveniles and adults are morphologically similar (hemimetaboly). Notably, among the most-ancestral hemimetabolous insects, dragonflies drastically alter their appearance from aquatic nymphs to aerial adults. In dragonflies, we showed that transcription factors <jats:italic>Kr-h1</jats:italic> and <jats:italic>E93</jats:italic> are essential for regulating metamorphosis as in other insects, while <jats:italic>broad</jats:italic> , the master gene for pupation in holometabolous insects, regulates a number of both nymph-specific genes and adult-specific genes, providing insight into what evolutionary trajectory the key transcription factor <jats:italic>broad</jats:italic> has experienced before ending up with governing pupation and holometaboly. </jats:p>

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