Opening up the Toolbox: Synthesis and Mechanisms of Phosphoramidates

  • Emeka J. Itumoh
    School of Chemical Sciences, The University of Auckland, 23 Symonds Street, Auckland 1010, New Zealand
  • Shailja Data
    School of Chemical Sciences, The University of Auckland, 23 Symonds Street, Auckland 1010, New Zealand
  • Erin M. Leitao
    School of Chemical Sciences, The University of Auckland, 23 Symonds Street, Auckland 1010, New Zealand

説明

<jats:p>This review covers the main synthetic routes to and the corresponding mechanisms of phosphoramidate formation. The synthetic routes can be separated into six categories: salt elimination, oxidative cross-coupling, azide, reduction, hydrophosphinylation, and phosphoramidate-aldehyde-dienophile (PAD). Examples of some important compounds synthesized through these routes are provided. As an important class of organophosphorus compounds, the applications of phosphoramidate compounds, are also briefly introduced.</jats:p>

収録刊行物

  • Molecules

    Molecules 25 (16), 3684-, 2020-08-13

    MDPI AG

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