The Impact of Sex and Gender on Stroke

  • Kathryn M. Rexrode
    Division of Women’s Health, Department of Medicine, Brigham and Women’s Hospital, Boston, MA (K.M.R.).
  • Tracy E. Madsen
    Division of Sex and Gender in Emergency Medicine, Department of Emergency Medicine, Warren Alpert Medical School of Brown University, Providence, RI (T.E.M.).
  • Amy Y.X. Yu
    Department of Medicine (Neurology), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada (A.Y.X.Y.).
  • Cheryl Carcel
    Neurology Program, George Institute for Global Health, University of New South Wales, Sydney, Australia (C.C.).
  • Judith H. Lichtman
    Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT (J.H.L.).
  • Eliza C. Miller
    Division of Stroke and Cerebrovascular Disease, Department of Neurology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY (E.C.M.).

抄録

<jats:p>Women face a disproportionate burden of stroke mortality and disability. Biologic sex and sociocultural gender both contribute to differences in stroke risk factors, assessment, treatment, and outcomes. There are substantial differences in the strength of association of stroke risk factors, as well as female-specific risk factors. Moreover, there are differences in presentation, response to treatment, and stroke outcomes in women. This review outlines current knowledge of impact of sex and gender on stroke, as well as delineates research gaps and areas for future inquiry.</jats:p>

収録刊行物

  • Circulation Research

    Circulation Research 130 (4), 512-528, 2022-02-18

    Ovid Technologies (Wolters Kluwer Health)

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