A retrospect on antimicrobial potential of thiazole scaffold

  • Isha Mishra
    Department of Pharmacy, School of Pharmaceutical Sciences IFTM University Moradabad India
  • Raghav Mishra
    Department of Pharmacy, Institute of Pharmaceutical Research GLA University Mathura India
  • Somdutt Mujwar
    Department of Pharmacy, Institute of Pharmaceutical Research GLA University Mathura India
  • Phool Chandra
    Department of Pharmacy, School of Pharmaceutical Sciences IFTM University Moradabad India
  • Neetu Sachan
    Department of Pharmacy, School of Pharmaceutical Sciences IFTM University Moradabad India

説明

<jats:title>Abstract</jats:title><jats:p>Due to its appreciable diversity in biological actions, thiazole and its substituted components, a significant class of heterocyclic compounds has developed as an influential scaffold in the field of chemical sciences. The variability of thiazole core has been expressed through the effective instigation of its anticancer (Dasatinib, Tiazofurin), antiretroviral (Ritonavir, Brecanavir), antimicrobial (Sulfathiazole, Ravuconazole) and anti‐inflammatory (Fenclozic acid, Meloxicam) derivatives. This reasonable diversity in the physiological reaction pattern led many scientists to refine and develop new structural alternatives with much more efficient pharmacological action. This review is crucial for previous studies and projects to survey the antimicrobial activity of thiazole and thiazole related compounds to the mid of 2019.</jats:p>

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