Triterpenoid Saponins from the Fruits of <i>Symplocos lucida</i> as β‐Glucuronidase Inhibitors

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  • Reina Higashi
    Graduate School of Integrated Sciences for Life Hiroshima University 1-7-1 Kagamiyama Higashi-Hiroshima 739-8521 Japan
  • Emi Ohta
    Graduate School of Integrated Sciences for Life Hiroshima University 1-7-1 Kagamiyama Higashi-Hiroshima 739-8521 Japan
  • Hisashi Ômura
    Graduate School of Integrated Sciences for Life Hiroshima University 1-7-1 Kagamiyama Higashi-Hiroshima 739-8521 Japan
  • Mylene M. Uy
    Department of Chemistry Mindanao State University-Iligan Institute of Technology Iligan City 9200 Philippines
  • Shinji Ohta
    Graduate School of Integrated Sciences for Life Hiroshima University 1-7-1 Kagamiyama Higashi-Hiroshima 739-8521 Japan

抄録

<jats:title>Abstract</jats:title><jats:p>A new triterpenoid saponin and five known ones were isolated from the fruits of <jats:italic>Symplocos lucida</jats:italic> (Thunb.) Siebold & Zucc. Their structures were determined based on the results of spectroscopy analysis, chemical conversions, and X‐ray crystallographic analyses. The β‐glucuronidase‐inhibitory effects of the isolated and semi‐synthesized triterpenoid saponins were also examined.</jats:p>

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