Obesity and COVID-19: What are the Consequences?

  • Charlotte Steenblock
    Department of Medicine III, Universitätsklinikum Carl Gustav Carus, Dresden, Germany
  • Mohamed Hassanein
    Department of Diabetes and Endocrinology, Dubai Hospital, Dubai, United Arab Emirates
  • Emran G. Khan
    Endocrinology and Diabetology, King’s College Hospital London, Dubai, United Arab Emirates
  • Mohamad Yaman
    Building 6, Nesmah Technology, Dubai, United Arab Emirates
  • Margrit Kamel
    Center for Regenerative Therapies Dresden, Technische Universitat Dresden, Dresden, Germany
  • Mahmoud Barbir
    Department of Cardiology, Harefield Hospital, Harefield, United Kingdom of Great Britain and Northern Ireland
  • Dietrich E. Lorke
    Department of Anatomy and Cellular Biology, Khalifa University, Abu Dhabi, United Arab Emirates
  • Dean Everett
    Department of Pathology and Infectious Diseases, Khalifa University, Abu Dhabi, United Arab Emirates
  • Saqipi Bejtullah
    Research Unit, College Heimerer, Prishtina, Republic of Kosovo
  • Tobias Lohmann
    MK5, Städtisches Klinikum Dresden, Dresden, Germany
  • Uwe Lindner
    Internal Medicine II, Klinikum Chemnitz, Chemnitz, Germany
  • Ermal Tahirukaj
    Department of Medicine III, Universitätsklinikum Carl Gustav Carus, Dresden, Germany
  • Feras Jassim Jirjees
    College of Pharmacy, University of Sharjah, Sharjah, United Arab Emirates
  • Sameh S.M. Soliman
    College of Pharmacy, University of Sharjah, Sharjah, United Arab Emirates
  • Friederike Quitter
    Klinik für Kinder- und Jugendmedizin, Universitätsklinikum Carl Gustav Carus, Dresden, Germany
  • Stefan R. Bornstein
    Department of Medicine III, Universitätsklinikum Carl Gustav Carus, Dresden, Germany

抄録

<jats:title>Abstract</jats:title><jats:p>Obesity is an increasing health problem all over the world. In combination with the current COVID-19 pandemic, this has turned into a massive challenge as individuals with overweight and obesity at all ages show a significant increase in their risk of getting severe COVID-19. Around 20% of all patients that were hospitalized for COVID-19 suffered from obesity alone, whereas obesity in combination with other metabolic comorbidities, such as type 2 diabetes and hypertension, account for up to 60% of all hospitalizations in relation to COVID-19. Therefore, it is of immense importance to put the spotlight on the high incidence of obesity present already in childhood both by changing the individual minds and by encouraging politicians and the whole society to commence preventive interventions for achieving a better nutrition for all social classes all over the world. In the current review, we aim to explain the different pathways and mechanisms that are responsible for the increased risk of severe COVID-19 in people with overweight and obesity. Furthermore, we discuss how the pandemic has led to weight gains in many people during lockdown. At the end, we discuss the importance of preventing such an interface between a non-communicable disease like obesity and a communicable disease like COVID-19 in the future.</jats:p>

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