PROTACs: past, present and future

DOI Web Site 2 Citations
  • Ke Li
    Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut 06511, USA
  • Craig M. Crews
    Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut 06511, USA

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<jats:p>This review highlights important milestones in the evolution of PROTACs, briefly discusses recent lessons about targeted protein degradation, and conjectures on the efforts still needed to expand the toolbox for PROTAC discovery.</jats:p>

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