Maintaining Normal Blood Pressure Across the Life Course

  • Shakia T. Hardy
    From the Department of Epidemiology (S.T.H., S.S., O.P.A., P.M.), University of Alabama at Birmingham, Birmingham, AL
  • Swati Sakhuja
    From the Department of Epidemiology (S.T.H., S.S., O.P.A., P.M.), University of Alabama at Birmingham, Birmingham, AL
  • Byron C. Jaeger
    Department of Biostatistics (B.C.J.), University of Alabama at Birmingham, Birmingham, AL
  • Suzanne Oparil
    Department of Medicine, Division of Cardiovascular Disease, University of Alabama at Birmingham (S.O.)
  • Oluwasegun P. Akinyelure
    From the Department of Epidemiology (S.T.H., S.S., O.P.A., P.M.), University of Alabama at Birmingham, Birmingham, AL
  • Tanya M. Spruill
    Department of Population Health, NYU Grossman School of Medicine, New York, NY (T.M.S., M.B.)
  • Jolaade Kalinowski
    Department of Human Development and Family Sciences, University of Connecticut, Storrs (J.K.)
  • Mark Butler
    Department of Population Health, NYU Grossman School of Medicine, New York, NY (T.M.S., M.B.)
  • D. Edmund Anstey
    Department of Medicine, Columbia University Irving Medical Center, New York, NY (D.E.A., D.S.)
  • Tali Elfassy
    Department of Medicine, University of Miami, FL (T.E.)
  • Gabriel S. Tajeu
    Department of Health Services Administration and Policy, Temple University, Philadelphia, PA (G.S.T.)
  • Norrina B. Allen
    Department of Preventive Medicine, Northwestern University, Chicago, IL (N.B.A., O.R.)
  • Orna Reges
    Department of Preventive Medicine, Northwestern University, Chicago, IL (N.B.A., O.R.)
  • Mario Sims
    Department of Medicine, University of Mississippi Medical Center, Jackson, MS (M.S.).
  • Daichi Shimbo
    Department of Medicine, Columbia University Irving Medical Center, New York, NY (D.E.A., D.S.)
  • Paul Muntner
    From the Department of Epidemiology (S.T.H., S.S., O.P.A., P.M.), University of Alabama at Birmingham, Birmingham, AL

書誌事項

タイトル別名
  • The JHS

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説明

<jats:p>Although mean blood pressure (BP) increases with age, there may be a subset of individuals whose BP does not increase with age. Characterizing the population that maintains normal BP could inform hypertension prevention efforts. We determined the proportion of Jackson Heart Study participants that maintained normal BP at 3 visits over a median of 8 years. Normal BP was defined as systolic BP <120 mm Hg and diastolic BP <80 mm Hg without antihypertensive medication. We identified lifestyle and psychosocial factors associated with maintaining normal BP and calculated the incidence rate for cardiovascular disease (CVD). Overall, 757 of 3432 participants (22.1%) had normal BP at baseline, and 262 of these participants (34.6%) maintained normal BP. Among participants with normal BP at baseline, normal body mass index (risk ratio [RR] 1.37 [95% CI, 1.08–1.75]), ideal physical activity (RR, 1.28 [95% CI, 0.99–1.65]), and never smoking (RR, 1.48 [95% CI, 0.99–2.20]) at baseline were associated with maintaining normal BP. Maintaining normal body mass index (RR, 1.42 [95% CI, 1.10–1.84]) and ideal physical activity (RR, 1.51 [95% CI, 1.18–1.94]) at all study visits were associated with maintaining normal BP. The cardiovascular disease incidence rate was 4.5, 6.3, and 16.4 per 1000 person-years among participants who maintained normal BP, had normal BP at baseline but did not maintain normal BP, and had elevated BP or hypertension at baseline, respectively, over 5.9 years of follow-up. These data suggest that maintaining normal body mass index and ideal physical activity are potential approaches for African American adults to maintain normal BP.</jats:p>

収録刊行物

  • Hypertension

    Hypertension 77 (5), 1490-1499, 2021-05

    Ovid Technologies (Wolters Kluwer Health)

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