An Updated Review of Macro, Micro, and Nanostructured Hydrogels for Biomedical and Pharmaceutical Applications

DOI Web Site 被引用文献2件
  • Caroline S. A. de Lima
    Nuclear and Energy Research Institute, IPEN-CNEN/SP, Av. Prof. Lineu Prestes, No. 2242, Cidade Universitária, São Paulo 05508-000, Brazil
  • Tatiana S. Balogh
    Nuclear and Energy Research Institute, IPEN-CNEN/SP, Av. Prof. Lineu Prestes, No. 2242, Cidade Universitária, São Paulo 05508-000, Brazil
  • Justine P. R. O. Varca
    Nuclear and Energy Research Institute, IPEN-CNEN/SP, Av. Prof. Lineu Prestes, No. 2242, Cidade Universitária, São Paulo 05508-000, Brazil
  • Gustavo H. C. Varca
    Nuclear and Energy Research Institute, IPEN-CNEN/SP, Av. Prof. Lineu Prestes, No. 2242, Cidade Universitária, São Paulo 05508-000, Brazil
  • Ademar B. Lugão
    Nuclear and Energy Research Institute, IPEN-CNEN/SP, Av. Prof. Lineu Prestes, No. 2242, Cidade Universitária, São Paulo 05508-000, Brazil
  • Luis A. Camacho-Cruz
    Departamento de Química de Radiaciones y Radioquímica, Instituto de Ciencias Nucleares, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, México CDMX 04510, Mexico
  • Emilio Bucio
    Departamento de Química de Radiaciones y Radioquímica, Instituto de Ciencias Nucleares, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, México CDMX 04510, Mexico
  • Slawomir S. Kadlubowski
    Institute of Applied Radiation Chemistry (IARC), Lodz University of Technology, Wroblewskiego No. 15, 93-590 Lodz, Poland

書誌事項

公開日
2020-10-15
権利情報
  • https://creativecommons.org/licenses/by/4.0/
DOI
  • 10.3390/pharmaceutics12100970
公開者
MDPI AG

説明

<jats:p>Hydrogels are materials with wide applications in several fields, including the biomedical and pharmaceutical industries. Their properties such as the capacity of absorbing great amounts of aqueous solutions without losing shape and mechanical properties, as well as loading drugs of different nature, including hydrophobic ones and biomolecules, give an idea of their versatility and promising demand. As they have been explored in a great number of studies for years, many routes of synthesis have been developed, especially for chemical/permanent hydrogels. In the same way, stimuli-responsive hydrogels, also known as intelligent materials, have been explored too, enhancing the regulation of properties such as targeting and drug release. By controlling the particle size, hydrogel on the micro- and nanoscale have been studied likewise and have increased, even more, the possibilities for applications of the so-called XXI century materials. In this paper, we aimed to produce an overview of the recent studies concerning methods of synthesis, biomedical, and pharmaceutical applications of macro-, micro, and nanogels.</jats:p>

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