Exploring the Underlying Genetics of Craniofacial Morphology through Various Sources of Knowledge
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- Jasmien Roosenboom
- Department of Neurosciences, Experimental Otorhinolaryngology, KU Leuven, Herestraat 49, P.O. Box 721, 3000 Leuven, Belgium
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- Greet Hens
- Department of Neurosciences, Experimental Otorhinolaryngology, KU Leuven, Herestraat 49, P.O. Box 721, 3000 Leuven, Belgium
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- Brooke C. Mattern
- Department of Anthropology, Penn State University, 409 Carpenter Building, University Park, PA 16802, USA
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- Mark D. Shriver
- Department of Anthropology, Penn State University, 409 Carpenter Building, University Park, PA 16802, USA
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- Peter Claes
- Medical Image Computing, ESAT/PSI, Department of Electrical Engineering, KU Leuven, Medical Imaging Research Center, Herestraat 49, P.O. Box 7003, 3000 Leuven, Belgium
Description
<jats:p>The craniofacial complex is the billboard of sorts containing information about sex, health, ancestry, kinship, genes, and environment. A thorough knowledge of the genes underlying craniofacial morphology is fundamental to understanding craniofacial biology and evolution. These genes can also provide an important foundation for practical efforts like predicting faces from DNA and phenotype-based facial diagnostics. In this work, we focus on the various sources of knowledge regarding the genes that affect patterns of craniofacial development. Although tremendous successes recently have been made using these sources in both methodology and biology, many challenges remain. Primary among these are precise phenotyping techniques and efficient modeling methods.</jats:p>
Journal
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- BioMed Research International
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BioMed Research International 2016 1-9, 2016
Hindawi Limited
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Details 詳細情報について
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- CRID
- 1360017287819119360
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- ISSN
- 23146141
- 23146133
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- Data Source
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- Crossref