Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L

  • Anneliese S. Ashhurst
    School of Chemistry, The University of Sydney, Sydney, NSW2006, Australia
  • Arthur H. Tang
    School of Chemistry, The University of Sydney, Sydney, NSW2006, Australia
  • Pavla Fajtová
    Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, California92093, United States
  • Michael C. Yoon
    Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, California92093, United States
  • Anupriya Aggarwal
    Kirby Institute, University of New South Wales, Sydney, NSW2052, Australia
  • Max J. Bedding
    School of Chemistry, The University of Sydney, Sydney, NSW2006, Australia
  • Alexander Stoye
    School of Chemistry, The University of Sydney, Sydney, NSW2006, Australia
  • Laura Beretta
    Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, California92093, United States
  • Dustin Pwee
    Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, California92093, United States
  • Aleksandra Drelich
    Department of Microbiology and Immunology, University of Texas, Medical Branch, 3000 University Boulevard, Galveston, Texas77755-1001, United States
  • Danielle Skinner
    Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, California92093, United States
  • Linfeng Li
    Department of Biochemistry and Biophysics, Texas A&M University, 301 Old Main Drive, College Station, Texas77843, United States
  • Thomas D. Meek
    Department of Biochemistry and Biophysics, Texas A&M University, 301 Old Main Drive, College Station, Texas77843, United States
  • James H. McKerrow
    Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, California92093, United States
  • Vivian Hook
    Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, California92093, United States
  • Chien-Te Tseng
    Department of Microbiology and Immunology, University of Texas, Medical Branch, 3000 University Boulevard, Galveston, Texas77755-1001, United States
  • Mark Larance
    Charles Perkins Centre and School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW2006, Australia
  • Stuart Turville
    Kirby Institute, University of New South Wales, Sydney, NSW2052, Australia
  • William H. Gerwick
    Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, California92093, United States
  • Anthony J. O’Donoghue
    Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, California92093, United States
  • Richard J. Payne
    School of Chemistry, The University of Sydney, Sydney, NSW2006, Australia

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