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- Yongzheng Xing
- Department of Chemistry, Institute for Structural and Molecular Biology University College London London WC1H 0AJ UK
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- Alexia Rottensteiner
- Department of Chemistry, Institute for Structural and Molecular Biology University College London London WC1H 0AJ UK
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- Jonah Ciccone
- Department of Chemistry, Institute for Structural and Molecular Biology University College London London WC1H 0AJ UK
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- Stefan Howorka
- Department of Chemistry, Institute for Structural and Molecular Biology University College London London WC1H 0AJ UK
抄録
<jats:title>Abstract</jats:title><jats:p>Membrane‐spanning nanopores are used in label‐free single‐molecule sensing and next‐generation portable nucleic acid sequencing, and as powerful research tools in biology, biophysics, and synthetic biology. Naturally occurring protein and peptide pores, as well as synthetic inorganic nanopores, are used in these applications, with their limitations. The structural and functional repertoire of nanopores can be considerably expanded by functionalising existing pores with DNA strands and by creating an entirely new class of nanopores with DNA nanotechnology. This review outlines progress in this area of functional DNA nanopores and outlines developments to open up new applications.</jats:p>
収録刊行物
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- Angewandte Chemie International Edition
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Angewandte Chemie International Edition 62 (33), 2023-05-23
Wiley