説明
<jats:title>Abstract</jats:title> <jats:p>DNA polymerases are the fundamental enzymes that synthesize cellular DNA to produce two identical daughter chromosomes. Cellular DNA polymerases in conjunction with DNA repair enzymes play critical roles for the transmission and maintenance of error-free genetic information from one generation to the next. In the last decade, genetic studies in yeast, biochemical studies of in vitro replication of the simain virus 40 (SV40) origin-containing DNA, and isolation of genes and cDNAs of DNA polymerases from budding yeast, fission yeasts, and mammalian cells led to the identification of five distinct DNA template-dependent DNA polymerases, named polymerase α, β, γ, δ, and ε(1,2).</jats:p>
収録刊行物
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- Eukaryotic DNA Replication
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Eukaryotic DNA Replication 67-92, 1999-02-18
Oxford University PressOxford