Covid‐19 and diabetes mellitus: unveiling the interaction of two pandemics
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- Ernesto Maddaloni
- Department of Experimental Medicine Sapienza University of Rome Rome Italy
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- Raffaella Buzzetti
- Department of Experimental Medicine Sapienza University of Rome Rome Italy
書誌事項
- 公開日
- 2020-04-13
- 権利情報
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- http://onlinelibrary.wiley.com/termsAndConditions#vor
- DOI
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- 10.1002/dmrr.3321
- 公開者
- Wiley
この論文をさがす
説明
<jats:title>Abstract</jats:title><jats:p>A novel RNA betacoronavirus causing coronavirus disease 2019 (Covid‐19) has now been declared pandemic disease by WHO. Guo et al published the first report of biochemical features in patients with diabetes and the further risk that this disease can determine to the progression of Covid‐19. Among different cytokines found significantly higher in patients with diabetes compared to those without, Interleukin‐6 (IL‐6), which is already increased in conditions of chronic inflammation, may play a more deleterious role in Covid‐19 infection. Targeting the overexpression of Il‐6 effects with a monoclonal antibody against IL‐6 receptor or using Janus Kinase inhibitors may be particularly helpful for treatment of Covid‐19 pneumonia in diabetes.</jats:p>
収録刊行物
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- Diabetes/Metabolism Research and Reviews
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Diabetes/Metabolism Research and Reviews 36 (7), 2020-04-13
Wiley