Insight into the function of voltage-sensing phosphatase in hindgut-derived pseudoplacenta of a viviparous teleost <i>Xenotoca eiseni</i>

  • Adisorn Ratanayotha
    Laboratory of Integrative Physiology, Department of Physiology, Graduate School of Medicine, Osaka University, Osaka, Japan
  • Atsuo Iida
    Department of Animal Sciences, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan
  • Jumpei Nomura
    Department of Animal Sciences, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan
  • Eiichi Hondo
    Department of Animal Sciences, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan
  • Yasushi Okamura
    Laboratory of Integrative Physiology, Department of Physiology, Graduate School of Medicine, Osaka University, Osaka, Japan
  • Takafumi Kawai
    Laboratory of Integrative Physiology, Department of Physiology, Graduate School of Medicine, Osaka University, Osaka, Japan

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説明

<jats:p> We investigate the voltage-sensing phosphatase (VSP) in Xenotoca eiseni, a viviparous fish whose intraovarian embryos utilize trophotaenia for nutrient absorption. Although X. eiseni VSP (Xe-VSP) shares key features with known VSPs, its distinct voltage sensitivity arises from species-specific amino acid variation. Xe-VSP in trophotaenia epithelium suggests its involvement in nutrient absorption, similar to VSP in zebrafish enterocytes and potentially in species with similar absorptive cells. Our findings highlight the potential role of VSP across species. </jats:p>

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