Measuring fluctuating dynamics of sparsely crosslinked actin gels with dual-feedback nonlinear microrheology

  • Kenji Nishizawa
    Department of Physics, The University of Tokyo, Tokyo 113-8654, Japan
  • Natsuki Honda
    Department of Physics, Kyushu University, Fukuoka 819-0395, Japan
  • Shono Inokuchi
    Department of Physics, Kyushu University, Fukuoka 819-0395, Japan
  • Hiroyuki Ebata
    Department of Physics, Kyushu University, Fukuoka 819-0395, Japan
  • Takayuki Ariga
    Graduate School of Frontier Biosciences, Osaka University, Suita 565-0871, Japan
  • Daisuke Mizuno
    Department of Physics, Kyushu University, Fukuoka 819-0395, Japan

書誌事項

公開日
2023-09-06
資源種別
journal article
権利情報
  • https://link.aps.org/licenses/aps-default-license
  • https://link.aps.org/licenses/aps-default-accepted-manuscript-license
DOI
  • 10.1103/physreve.108.034601
公開者
American Physical Society (APS)

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説明

We investigate the fluctuating dynamics of colloidal particles in weakly crosslinked F-actin networks with optical-trap-based microrheology. Using the dual-feedback technology, embedded colloidal particles were stably forced beyond the linear regime in a manner that does not suppress spontaneous fluctuations of particles. Upon forcing, a particle that was stably confined in a cage made of the network's crosslinks started to intermittently jump to the next caging microenvironments. By investigating the statistics of the jump dynamics, we discuss how heterogeneous relaxations observed in equilibrium systems became homogeneous when similar jumps were activated under constant forcing beyond the linear regime.

収録刊行物

  • Physical Review E

    Physical Review E 108 (3), 2023-09-06

    American Physical Society (APS)

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