Remdesivir and GS-441524 Retain Antiviral Activity against Delta, Omicron, and Other Emergent SARS-CoV-2 Variants
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- Jared Pitts
- Gilead Sciences, Inc., Foster City, California, USA
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- Jiani Li
- Gilead Sciences, Inc., Foster City, California, USA
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- Jason K. Perry
- Gilead Sciences, Inc., Foster City, California, USA
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- Venice Du Pont
- Gilead Sciences, Inc., Foster City, California, USA
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- Nicholas Riola
- Gilead Sciences, Inc., Foster City, California, USA
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- Lauren Rodriguez
- Gilead Sciences, Inc., Foster City, California, USA
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- Xianghan Lu
- Gilead Sciences, Inc., Foster City, California, USA
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- Chaitanya Kurhade
- Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, USA
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- Xuping Xie
- Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, USA
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- Gregory Camus
- Gilead Sciences, Inc., Foster City, California, USA
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- Savrina Manhas
- Gilead Sciences, Inc., Foster City, California, USA
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- Ross Martin
- Gilead Sciences, Inc., Foster City, California, USA
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- Pei-Yong Shi
- Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, USA
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- Tomas Cihlar
- Gilead Sciences, Inc., Foster City, California, USA
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- Danielle P. Porter
- Gilead Sciences, Inc., Foster City, California, USA
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- Hongmei Mo
- Gilead Sciences, Inc., Foster City, California, USA
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- Evguenia Maiorova
- Gilead Sciences, Inc., Foster City, California, USA
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- John P. Bilello
- Gilead Sciences, Inc., Foster City, California, USA
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説明
<jats:p>Genetic variation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in the emergence and rapid spread of multiple variants throughout the pandemic, of which Omicron is currently the predominant variant circulating worldwide. SARS-CoV-2 variants of concern/variants of interest (VOC/VOI) have evidence of increased viral transmission, disease severity, or decreased effectiveness of vaccines and neutralizing antibodies.</jats:p>
収録刊行物
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- Antimicrobial Agents and Chemotherapy
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Antimicrobial Agents and Chemotherapy 66 (6), e0022222-, 2022-06-21
American Society for Microbiology
