Changes in cognitive functioning after COVID‐19: A systematic review and meta‐analysis
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- William Carroll
- Department of Neurology Sir Charles Gairdner Hospital and Center for Neuromuscular and Neurological Disorders Perron Institute Perth Western Australia Australia
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- Andrea Sylvia Winkler
- Department of Neurology Center for Global Health Klinikum rechts der Isar Technical University of Munich Munich, Germany and Centre for Global Health Institute of Health and Society University of Oslo Oslo Norway
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- Francesca Mangialasche
- Division of Clinical Geriatrics Department of Neurobiology, Care Sciences and Society Karolinska Institutet Stockholm Sweden
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- Erica Westenberg
- Department of Neurology Center for Global Health Klinikum rechts der Isar Technical University of Munich Munich Germany
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- Ricardo F. Allegri
- Department of Cognitive Neurology Fleni Buenos Aires Argentina
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- David García‐Azorín
- Department of Neurology Hospital Clínico Universitario de Valladolid Valladolid Spain
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- Ismael Calandri
- Department of Cognitive Neurology Fleni Buenos Aires Argentina
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- Ettore Beghi
- Department of Neuroscience Instituto di Ricerche Farmacologiche Mario Negri IRCCS Milan Italy
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- Miia Kivipelto
- Division of Clinical Geriatrics Department of Neurobiology, Care Sciences and Society Karolinska Institutet Stockholm Sweden
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- Lucia Crivelli
- Department of Cognitive Neurology Fleni Buenos Aires Argentina
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- Jennifer Frontera
- Department of Neurology NYU Grossman School of Medicine New York New York USA
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- Katie Palmer
- Division of Clinical Geriatrics Department of Neurobiology, Care Sciences and Society Karolinska Institutet Stockholm Sweden
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- Alla Guekht
- Moscow Research and Clinical Center for Neuropsychiatry Russia, and Pirogov Russian National Research University Moscow Russia
書誌事項
- 公開日
- 2022-03-17
- 権利情報
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- http://onlinelibrary.wiley.com/termsAndConditions#vor
- DOI
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- 10.1002/alz.12644
- 公開者
- Wiley
この論文をさがす
説明
<jats:title>Abstract</jats:title><jats:sec><jats:title>Introduction</jats:title><jats:p>We conducted a systematic review and meta‐analysis of the cognitive effects of coronavirus disease 2019 (COVID‐19) in adults with no prior history of cognitive impairment.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Searches in Medline/Web of Science/Embase from January 1, 2020, to December 13, 2021, were performed following Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines. A meta‐analysis of the Montreal Cognitive Assessment (MoCA) total score comparing recovered COVID‐19 and healthy controls was performed.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Oof 6202 articles, 27 studies with 2049 individuals were included (mean age = 56.05 years, evaluation time ranged from the acute phase to 7 months post‐infection). Impairment in executive functions, attention, and memory were found in post‐COVID‐19 patients. The meta‐analysis was performed with a subgroup of 290 individuals and showed a difference in MoCA score between post‐COVID‐19 patients versus controls (mean difference = −0.94, 95% confidence interval [CI] −1.59, −0.29; <jats:italic>P</jats:italic> = .0049).</jats:p></jats:sec><jats:sec><jats:title>Discussion</jats:title><jats:p>Patients recovered from COVID‐19 have lower general cognition compared to healthy controls up to 7 months post‐infection.</jats:p></jats:sec>
収録刊行物
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- Alzheimer's & Dementia
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Alzheimer's & Dementia 18 (5), 1047-1066, 2022-03-17
Wiley
