Design and Synthesis of Amphiphilic Xanthone-Based, Membrane-Targeting Antimicrobials with Improved Membrane Selectivity

  • Hanxun Zou
    Singapore Eye Research Institute, 11 Third Hospital Avenue, Singapore 168751, Singapore
  • Jun-Jie Koh
    Singapore Eye Research Institute, 11 Third Hospital Avenue, Singapore 168751, Singapore
  • Jianguo Li
    Singapore Eye Research Institute, 11 Third Hospital Avenue, Singapore 168751, Singapore
  • Shengxiang Qiu
    Program for Natural Products Chemical Biology, Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, the Chinese Academy of Sciences, Guangzhou, China
  • Thet Tun Aung
    Singapore Eye Research Institute, 11 Third Hospital Avenue, Singapore 168751, Singapore
  • Huifen Lin
    Singapore Eye Research Institute, 11 Third Hospital Avenue, Singapore 168751, Singapore
  • Rajamani Lakshminarayanan
    Singapore Eye Research Institute, 11 Third Hospital Avenue, Singapore 168751, Singapore
  • Xiaoping Dai
    Program for Natural Products Chemical Biology, Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, the Chinese Academy of Sciences, Guangzhou, China
  • Charles Tang
    Department of Pathology, Singapore General Hospital, Singapore 169608, Singapore
  • Fang Hui Lim
    Singapore Eye Research Institute, 11 Third Hospital Avenue, Singapore 168751, Singapore
  • Lei Zhou
    Singapore Eye Research Institute, 11 Third Hospital Avenue, Singapore 168751, Singapore
  • Ai Ling Tan
    Department of Pathology, Singapore General Hospital, Singapore 169608, Singapore
  • Chandra Verma
    Singapore Eye Research Institute, 11 Third Hospital Avenue, Singapore 168751, Singapore
  • Donald T. H. Tan
    Singapore Eye Research Institute, 11 Third Hospital Avenue, Singapore 168751, Singapore
  • Hardy Sze On Chan
    Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore
  • Padmanabhan Saraswathi
    Singapore Eye Research Institute, 11 Third Hospital Avenue, Singapore 168751, Singapore
  • Derong Cao
    School of Chemistry and Chemical Engineering, State Key Lab of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510641, China
  • Shouping Liu
    Singapore Eye Research Institute, 11 Third Hospital Avenue, Singapore 168751, Singapore
  • Roger W. Beuerman
    Singapore Eye Research Institute, 11 Third Hospital Avenue, Singapore 168751, Singapore

書誌事項

公開日
2013-03-13
DOI
  • 10.1021/jm301683j
公開者
American Chemical Society (ACS)

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