Design of a SNARF-based Ratiometric Fluorescent Probe for Esterase

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  • Eiji Nakata
    Department of Life System, Institute of Technology and Science, The University of Tokushima
  • Yoshihiro Yukimachi
    Department of Life System, Institute of Technology and Science, The University of Tokushima
  • Yoshijiro Nazumi
    Department of Life System, Institute of Technology and Science, The University of Tokushima
  • Yoshihiro Uto
    Department of Life System, Institute of Technology and Science, The University of Tokushima
  • Toshihiro Hashimoto
    Faculty of Pharmaceutical Sciences, Tokushima Bunri University
  • Yasuko Okamoto
    Faculty of Pharmaceutical Sciences, Tokushima Bunri University
  • Hitoshi Hori
    Department of Life System, Institute of Technology and Science, The University of Tokushima

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<jats:title>Abstract</jats:title> <jats:p>A novel ratiometric fluorescent probe for esterase has been developed based on the SNARF scaffold. The new SNARF derivative was used to monitor the activity of porcine liver esterase by ratiometric emission spectrum change.</jats:p>

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  • Chemistry Letters

    Chemistry Letters 39 (7), 734-735, 2010-06-05

    Oxford University Press (OUP)

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