β-Amination of Saturated Nitriles through Palladium-catalyzed Dehydrogenation, 1,4-Addition, and Re-dehydrogenation

  • Satoshi Ueno
    Department of Chemistry, Graduate School of Sciences, Kyushu University
  • Ryohei Maeda
    Department of Chemistry, Graduate School of Sciences, Kyushu University
  • Shohei Yasuoka
    Department of Chemistry, Graduate School of Sciences, Kyushu University
  • Ryoichi Kuwano
    Department of Chemistry, Graduate School of Sciences, Kyushu University

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Description

<jats:title>Abstract</jats:title> <jats:p>Amination at the β-position of 2-arylpropionitriles through catalytic dehydrogenation occurred by using [PdCl2(PMe3)2] catalyst and bromobenzene. This is the first catalytic reaction involving the direct dehydrogenation of saturated nitriles.</jats:p>

Journal

  • Chemistry Letters

    Chemistry Letters 42 (1), 40-42, 2012-12-22

    Oxford University Press (OUP)

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